
Heteroplasmic de novo MT-ND5 truncating mutations: Implications for mitochondrial function in oncogenesis
GA, UNITED STATES, May 19, 2025 /EINPresswire.com/ -- With mitochondrial DNA (mtDNA) base editing tools, this study controlled the nuclear background to investigate the causal effect of mtDNA mutations. Co-existence of wild-type and mutant mtDNA …